Best Seller

A.G.E. Interrupter Advanced Cream

Anti-wrinkle face cream

A.G.E. Interrupter Advanced is a potent wrinkle cream that helps reverse visible signs of aging, inc ... Read full description

Best Seller

RECOMMENDED FOR

• Dry

• Combination

• Sensitive

• Normal

• Aging

A.G.E. Interrupter Advanced Cream

Anti-wrinkle face cream

48ml - US

48ml - INTL

A.G.E. Interrupter Advanced Benefits

Visibly corrects a range of wrinkle types including fine lines, deep wrinkles and location-specific creases

Helps restore skin’s density, which is known to decline as glycation degrades skin’s collage

Visibly reduces discoloration for a healthier looking complexion

Complements collagen remodeling procedure RF microneedling for 3x better lifting results

Helps reverse collagen glycation, a process known to visibly age skin, by 33%

Delivers rich all-day hydration, with a luxurious, satin finish

Free of parabens, drying alcohol, and dyes

A.G.E. Interrupter Advanced Product Details

A.G.E. Interrupter Advanced is a potent wrinkle cream that helps reverse visible signs of aging, including fine lines and deep wrinkles, caused by collagen decline and glycation.

Backed by more than 15 years of glycation research and expertise, A.G.E. Interrupter Advanced is a potent anti-wrinkle cream that helps correct and defend against visible signs of aging. Formulated with 18% concentrated Proxylane^TM, 4.25% wild fruit flavonoids and 0.1% glycyrrhetinic acid, this breakthrough anti-aging moisturizer is clinically proven to help reverse skin-aging glycation by up to 33%. A.G.E. Interrupter Advanced contains a high performance formula that is clinically shown to smooth visible lines and deep wrinkles in five facial zones, reduce visible discoloration, and restore skin density. Physician tested to complement RF microneedling treatments for 3x better lifting results in 12 weeks. This advanced anti-aging cream is suitable for GLP-1 patients. A.G.E. Interrupter Advanced, paired with A.G.E. Interrupter Ultra Serum and ultrasound lifting treatments, is physician-tested to reverse skin laxity by 44% in 12 weeks.

HOW TO USE >

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A.G.E. Interrupter Advanced
SCIENCE + PROOF

Visible Results

After 12 weeks, A.G.E. Interrupter Advanced improved
attributes associated with skin aging and glycation, including
lines and deep wrinkles in five facial zones.

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14%

Reduction in
global fine lines

11.5%

Reduction in
forehead wrinkles

11%

Reduction in
nasolabial folds

7%

Reduction in
marionette wrinkles

7%

Reduction in
glabellar wrinkles

7%

Reduction in
crow's feet lines

Visible Results

After 12 weeks, A.G.E. Interrupter Advanced improved
attributes associated with skin aging and glycation, including
lines and deep wrinkles in five facial zones.

14%

Reduction in
global fine lines

11.5%

Reduction in
forehead wrinkles

11%

Reduction in
nasolabial folds

7%

Reduction in
marionette wrinkles

7%

Reduction in
glabellar wrinkles

7%

Reduction in
crow's feet lines

👁 SEE OUR PROTOCOL

The Science Behind
A.G.E. Interrupter Advanced

What is Skin Glycation?

Glycation is natural process that accelerates visible signs of aging. During the glycation process, excess sugars bind to skin-supporting proteins (like collagen and elastin) and form advanced glycation end-products (A.G.E.s). A.G.E.s weaken collagen, leading to wrinkles and laxity.

Signs of Glycation

Wrinkling and crepiness
Loss of firmness
Dull, sallow complexion

Glycation DOs and DON'Ts

DO: Wear Sunscreen
Protect skin from UV damage and oxidative stress by applying broad-spectrum sunscreen daily.

DO: Reduce Sugar
Alcohol consumption and high-sugar diets can promote the glycation process.

DON’T: Expose Skin to Smoke
Cigarette smoke deposits a myriad of chemicals onto the skin in addition to speeding up the glycation process.

A.G.E. Interrupter Advanced + RF Microneedling Treatments

Reverse visible signs of aging impacted by glycation by integrating energy-based treatments like RF microneedling. Together, A.G.E. Interrupter Advanced and skin-tightening RF microneedling treatments can help reverse the erosion elasticity and firmness caused by glycation with targeted deep-tissue wrinkle correction. A.G.E. Interrupter Advanced is physician tested to complement RF microneedling treatments and provide 3x better lifting results in 12 weeks.

A.G.E. Routine for GLP-1 Users

GLP-1 medications can contribute to accelerated visible aging, including loss of facial volume, diminished skin elasticity, and increased skin laxity. The A.G.E. routine, featuring A.G.E. Interrupter Advanced and A.G.E. Interrupter Ultra Serum, is physician-tested to reverse skin laxity for GLP-1 patients in just 4 weeks.

When combined with ultrasound lifting procedures, A.G.E. physician tests showed a reduction in skin laxity, facial laxity, and marionette lines after 12 weeks.

20% average reduction in skin laxity vs. control
44% reduction in facial laxity
34% reduction in marionette lines
84% of participants reported their skin appeared visibly tighter

Key Ingredients

Paraben-Free

Dye-Free

Drying Alcohol-Free

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18% Concentrated Proxylane

Helps support skin’s integrity and correct visible signs of aging, like wrinkles and laxity.

4.25% Wild Fruit Flavonoids

Combination of blueberry and pomegranate extracts help reduce oxidative stresCB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.

1% Glycyrrhetinic Acid

Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

3% Hepes

Activates natural enzymes in skin to promote even cell turnover while hydrating skin.

1% Niacinamide

Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.

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How to Use A.G.E. Interrupter Advanced

1

Prep + Dispense

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest. With this potent formula, only a small amount is needed.

2

Apply + Complete

If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.